Night time bp recorded by abpm has emerged as a better predictor of total mortality stroke and cardiovascular death in patients with hypertension and a history of cvd than either day time abpm or in office bp measurements 10 normally bp varies with the circadian clock it is higher during the day time and decreases by 10 to 20 during.

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Inform patients and or their caregivers that myrbetriq may cause urinary retention in adult patients with bladder outlet obstruction and in patients taking muscarinic antagonist medications for the treatment of oab advise patients to contact their physician if they experience these effects while taking myrbetriq.